Collagen metabolism in adjuvant-induced arthritis in the rat.
نویسندگان
چکیده
منابع مشابه
Collagen metabolism in adjuvant-induced arthritis in the rat.
The adjuvant arthritis of the rat is a systemic disease afflicting the musculoskeletal structures, accompanied by a number of visceral manifestations (Pearson, 1956; Pearson and Wood, 1959). It has been receiving considerable attention in studies of the factors that may influence the development and course of the rheumatic diseases in man (Leader, Gorham, and Wagner, 1967). This experimental ar...
متن کاملSynergy between adjuvant arthritis and collagen-induced arthritis in rats
Adjuvant arthritis (AA) in rats is susceptible to cell-mediated passive transfer. Collagen-induced arthritis (CIA) in rats is susceptible to passive transfer with antibody to type II collagen. We report here the development of strikingly severe arthritis in Lewis rats as the result of synergy between passively transferred antibody to type II collagen from rats with CIA and concanavalin A (Con A...
متن کاملT Cell Vaccination as a Tool in the Treatment of Collagen Induced Arthritis in Albino Rats
Background: The effectiveness of T cell vaccination has been demonstrated in a variety of animal models of both induced and spontaneous autoimmune diseases. Objective: The purpose of this study was to test the T cell vaccination protocol to treat and prevent collagen induced arthritis (CIA) in a rheumatoid arthritis model. Methods: CIA was induced by an intradermal injection of an artheritogen ...
متن کاملStudy on anti inflammatory effect of scorpion (Mesobuthus eupeus) venom in adjuvant-induced arthritis in rats
Rheumatoid arthritis is an autoimmune disease that causes chronic inflammation of the joints as well as other organs in the body. Adjuvant-induced arthritis models in inbred rats serve as relevant models for RA, having many clinical similarities to this disease. Using honey bee venom as a treatment for Rheumatoid arthritis is an ancient therapy in various parts of the world. However scorpion ve...
متن کاملEffect of Losartan in Complete Freund’s Adjuvant –Induced Arthritis in Rats
Rheumatoid arthritis (RA) is an autoimmune inflammatory disease characterized by joint infiltration and bone damage. The aim of the present study was to evaluate the beneficial effects of losartan in adjuvant-induced arthritis (AIA). Arthritis was induced in rats by subcutaneous injection of 0.2ml of Complete Freund’s adjuvant (CFA) in the planter surface of the hind paw. Arthritic rats were al...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Annals of the Rheumatic Diseases
سال: 1972
ISSN: 0003-4967
DOI: 10.1136/ard.31.4.334